Thomas Swan offers a wide range of complex and multi-step synthesis capabilities. Our aim is to provide a fast, flexible and confidential service. The following list details our current range of synthetic capabilities:
More than 50 years industrial experience in a broad range of polymerisation technologies
Experience in using dimethyl sulfate as alkylation agents plus use of Friedel Crafts alkylation chemistry at up to 1000tpa capactiy
Dedicated facility for industrial applications performed on a range of aromatic substrates at 500tpa capacity
Dedicated and multipurpose plants capable of performing these chemistries at volumes of upto 500tpa
Commercial scale halogenation capacity to 500tpa with the capability for cGMP manufacture. Specificity in chlorination and bromination up to 1500tpa capacity
A broad range of capabilities including Diels Alder, primarily for household, health and personal care industries that can be performed at volumes up to 300tpa
With the capacity to isomerise and isolate products by distillation can be performed at volumes up to 700tpa
Sulphonation of aromatic substrates and polyaromatic polymers this chemistry can be performed at volumes up to 500tpa
100tpa capacity at temperatures up to 270oc
25 years of experience in aromatic thiocyanation up to 500tpa
Commercial scale experience of a broad range of carbon and hetero atom oxidations
Several years of experience of diazotisation including hair and personal care product applications
For more than 30 years Thomas Swan has been at the forefront of cutting-edge innovative process engineering. Current commercial scale facilities include:
Commercial scale batch and continuous furnaces operating under inert conditions and up to 1000oC. This versatile equipment, in a state-of-the-art manufacturing environment, facilitates many specialist techniques including:
(batch and continuous)
Gas-solid reactions and other specific reactions including:
i. Reductions and Oxidations
ii. Drying and Calcination
ii. Catalyst processing and activation
Versatile pilot scale laboratories support not only the commercial scale operations, but also facilitate the production of validation quantities under highly controlled conditions. Facilities include:
i. Dissolution
ii. Controlled precipitation
Thomas Swan’s recent £200k investment in Analytical Development Services underlines how much we recognise the importance of performing analytical development and method verification. Synchronised perfectly with process development, this ensures all projects are delivered safely to an agreed specification and on time.
with FID detector, liquid and headspace injection techniques
Assistance with impurity profiling
with UV, Diode Array and Refractive Index dectection
with Refractive Index Detector
Useful for carbon hybridisation determination
Accurate measurement of mass loss vs temperature up to 1100 degrees C
Broad range elemental analysis to ppm levels
(Cone & Plate, Brookfield and PRS)
including auto-titration
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